2021年5月circRNA研究汇总-2（ 20210510-0516）

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主要内容

论文标题

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单位

1

CircMEMO1通过调节TCF21启动子甲基化和表达，调控肝细胞癌的进展和索拉非尼治疗的敏感性

CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity

Mol Cancer.

15.303

复旦大学附属中山医院等

2

健康和疾病的人类胎盘中RNA景观

The RNA landscape of the human placenta in health and disease

Nat Commun.

12.121

英国剑桥大学等

3

非编码RNA在糖尿病伤口研究的进展、前景和挑战

The progress, prospects, and challenges of the use of non-coding RNA for diabetic wounds

Mol Ther Nucleic Acids.Review

7.033

遵义医科大学等

4

环状RNA circACSL1通过miR-8055调节MAPK14表达来加重心肌炎症和心肌损伤

Circular RNA circACSL1 aggravated myocardial inflammation and myocardial injury by sponging miR-8055 and regulating MAPK14 expression

Cell Death Dis.

6.303

山东省立医院等

6

环状RNA在甲状腺癌中的新兴作用。

Emerging Roles of Circular RNAs in Thyroid Cancer

Front Cell Dev Biol.Review

5.202

中南大学湘雅医院等

7

环状RNA circSIPA1L1通过miR-411-5p/RAB9A信号传导途径促进骨肉瘤进展

Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway

Front Cell Dev Biol.

5.202

浙江大学医学院等

8

环状RNA circUbe2k通过使miR-149-5p/TGF-β2轴海绵化促进肝纤维化

Circular RNA circUbe2k promotes hepatic fibrosis via sponging miR-149-5p/TGF-尾2 axis

FASEB J.

4.965

安徽医科大学等

9

circ_0032822通过miR-141/EF3信号轴促进头颈部鳞状细胞癌细胞的增殖

The circ_0032822 Promotes the Proliferation of Head and Neck Squamous Cell Carcinoma Cells Through miR-141/EF3 Signaling Axis

Front Oncol.

4.849

连云港市第一人民医院等

10

环状RNA Plek通过调节脊髓损伤后的miR-135b-5p/TGF-βR1轴来促进纤维化激活

Circular RNA Plek promotes fibrogenic activation by regulating the miR-135b-5p/TGF-尾R1 axis after spinal cord injury

Aging (Albany NY).

4.833

山东齐鲁医院等

11

外体circRNA 0001445通过miRNA-127-5p/SNX5途径促进神经胶质瘤进展

Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway

Aging (Albany NY).

4.833

河北沧州市中心医院等

12

CircRNA_30032通过miRNA-96-5p/HBEGF/KRAS轴促进UUO模型小鼠的肾纤维化

CircRNA_30032 promotes renal fibrosis in UUO model mice via miRNA-96-5p/HBEGF/KRAS axis

Aging (Albany NY).

4.833

中南大学湘雅市第二医院等

13

非编码RNA调节胎盘滋养细胞功能并参与反复流产。

Non-Coding RNAs Regulate Placental Trophoblast Function and Participate in Recurrent Abortion

Front Pharmacol.Review

4.229

武汉人民医院等

14

circHIPK3的生物发生，细胞作用和生物标志物的价值

Biogenesis, cellular effects, and biomarker value of circHIPK3

Cancer Cell Int.Review

4.179

复旦大学附属妇产科医院等

15

CircRNA_2646作为ceRNA通过抑制miR-124/PLP2信号通路促进食管鳞状细胞癌的发展

CircRNA_2646 functions as a ceRNA to promote progression of esophageal squamous cell carcinoma via inhibiting miR-124/PLP2 signaling pathway

Cell Death Discov.

4.111

中山大学附属第一医院等

16

circSnx12通过靶向miR-224-5p参与心力衰竭期间的肥大症

circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p

Front Cardiovasc Med.

3.916

沈阳医学院等

17

环状RNA ZNF609通过调节miR-1224-3p/PLK1信号传导促进神经胶质瘤的恶性进展

Circular RNA ZNF609 promotes the malignant progression of glioma by regulating miR-1224-3p/PLK1 signaling

J Cancer.

3.568

南京医科大学附属儿童医院等

18

Hsa_circ_0091581通过海绵化miR-1243-5p调节RMI1促进神经胶质瘤进展

Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p

J Cancer.

3.568

南京脑科医院等

19

姜黄素类似物GL63通过circZNF83/miR-324-5p/CDK16轴使JAK2/STAT3信号通路失活，从而抑制肝细胞癌的恶性行为。

A curcumin analogue GL63 inhibits the malignant behaviors of hepatocellular carcinoma by inactivating the JAK2/STAT3 signaling pathway via the circZNF83/miR-324-5p/CDK16 axis

J Gastroenterol Hepatol.

3.435

河北医科大学附属第一医院等

20

环状RNA ITCH是通过miR-106b-5p/PDCD4轴在透明细胞肾细胞癌转移中的肿瘤抑制因子

Circular RNA ITCH Is a Tumor Suppressor in Clear Cell Renal Cell Carcinoma Metastasis through miR-106b-5p/PDCD4 Axis

J Immunol Res.

3.329

淮安市第二人民医院等

21

circRNA作为败血症生物标志物的研究进展：综述

Research progress of circRNA as a biomarker of sepsis: a narrative review

Ann Transl Med.Review

3.298

南通大学附属医院等

22

Ferroptosis通过circ0097009/miR-1261/SLC7A11轴参与了肝细胞癌的进展

Ferroptosis is involved in the progression of hepatocellular carcinoma through the circ0097009/miR-1261/SLC7A11 axis

Ann Transl Med.

3.298

中山大学肿瘤防治中心等

23

环状RNA作为心血管疾病潜在生物标志物和治疗靶点

A narrative review of circular RNAs as potential biomarkers and therapeutic targets for cardiovascular diseases

Ann Transl Med.Review

3.298

上海同济医院等

24

用于研究白癜风发病机理的黑素细胞中潜在功能的circRNA-miRNA-mRNA调控网络的鉴定。

Identification of a Potentially Functional circRNA-miRNA-mRNA Regulatory Network in Melanocytes for Investigating Pathogenesis of Vitiligo

Front Genet.

3.257

广西壮族自治区人民医院等

25

外泌体Circ-XIAP通过调节miR-1182/TPD52轴促进前列腺癌中的多西他赛耐药。

Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis

Drug Des Devel Ther.

3.215

驻马店市中心医院等

26

m6A RNA甲基化在糖尿病性视网膜病变中的潜在作用

The potential role of m6A RNA methylation in diabetic retinopathy

Exp Eye Res.Review

3.011

印度化学生物学研究所

27

敲低circBFAR可以抑制miR-513a-3p/己糖激酶2轴，从而抑制胃癌的增殖和糖酵解

Knockdown of circBFAR inhibits proliferation and glycolysis in gastric cancer by sponging miR-513a-3p/hexokinase 2 axis

Biochem Biophys Res Commun.

2.987

解放军总医院等

28

胃癌衍生的外泌体通过靶向内皮细胞中的miR-29a/VEGF轴来介导circRNA的传递以促进血管生成

Gastric cancer derived exosomes mediate the delivery of circRNA to promote angiogenesis by targeting miR-29a/VEGF axis in endothelial cells

Biochem Biophys Res Commun.

2.985

天津医科大学肿瘤研究所等

29

CircRNA circ_POLA2在急性髓细胞性白血病（AML）中上调并通过抑制成熟miR-34a的产生促进细胞增殖

CircRNA circ_POLA2 is Upregulated in Acute Myeloid Leukemia (AML) and Promotes Cell Proliferation by Suppressing the Production of Mature miR-34a

Cancer Manag Res.

2.888

山东千佛山医院等

30

hsa_circ_0062019通过miR-195-5p/HMGA2轴促进前列腺癌细胞的增殖，迁移和侵袭

hsa_circ_0062019 promotes the proliferation, migration, and invasion of prostate cancer cells via the miR-195-5p/HMGA2 axis

Acta Biochim Biophys Sin (Shanghai).

2.836

安徽医科大学等

31

外泌体穿梭的Circ_0009910通过调节miR-5195-3p/GRB10轴来调节急性髓性白血病细胞的增殖，细胞周期和凋亡

Circ_0009910 shuttled by exosomes regulates proliferation, cell cycle and apoptosis of acute myeloid leukemia cells by regulating miR-5195-3p/GRB10 axis

Hematol Oncol.

2.834

武汉同济医院等

32

Circ_CHFR通过miR-149-5p/NRP2轴促进PDGF-BB诱导的VSMC增殖，侵袭和迁移

Circ_CHFR promotes PDGF-BB-induced proliferation, invasion and migration in VSMCs via miR-149-5p/NRP2 axis

J Cardiovasc Pharmacol.

2.599

西安医科大学附属第一医院等

33

环状RNA在干细胞分化中的作用：miRNA的海绵状作用

Circular RNAs in stem cell differentiation: a sponge-like role for miRNAs

Int J Med Sci.Review

2.522

中南大学湘雅第二医院等

34

has_circ_0071106可用作2型糖尿病的诊断标记

has_circ_0071106 can be used as a diagnostic marker for type 2 diabetes

Int J Med Sci.

2.522

广东药科大学等

35

环状RNA circFADS2在脓毒症中过表达，并通过抑制miR-15a-5p的成熟来抑制LPS诱导的肺细胞凋亡

Circular RNA circFADS2 is overexpressed in sepsis and suppresses LPS-induced lung cell apoptosis by inhibiting the maturation of miR-15a-5p

BMC Immunol.

2.497

解放军总医院等

36

环状RNA circ_GRHPR通过与RNA结合蛋白PCBP2的相互作用促进NSCLC细胞增殖和侵袭

The circular RNA circ_GRHPR promotes NSCLC cell proliferation and invasion via interactions with the RNA-binding protein PCBP2

Clin Exp Pharmacol Physiol.

2.457

上海瑞金医院等

37

CircAMD1通过海绵化miR-27a-3p在P63突变的人真皮成纤维细胞中调节增殖和胶原蛋白的合成

CircAMD1 regulates proliferation and collagen synthesis via sponging miR-27a-3p in P63-mutant human dermal fibroblasts

Differentiation.

2.392

中国医科大学附属盛京医院等

38

子痫前期环状RNA的鉴定和比较

Identification and comparison of circular RNAs in preeclampsia

PeerJ.

2.377

苏州市立医院等

39

环状RNA UBAP2通过miR-1244/MAP3K2轴促进前列腺癌细胞的增殖

Circular RNA UBAP2 promotes the proliferation of prostate cancer cells via the miR-1244/MAP3K2 axis

Oncol Lett.

2.313

新疆医科大学附属第一医院等

40

环状RNA circPVT1通过miR-137调节TRIAP1促进骨肉瘤细胞对阿霉素（DXR）的抗性

Circular RNA circPVT1 Contributes to Doxorubicin (DXR) Resistance of Osteosarcoma Cells by Regulating TRIAP1 via miR-137

Biomed Res Int.

2.279

吉林大学中日联谊医院等

41

胃癌患者环状RNA相关的三基因预后签名。

A Robust Circular RNA-Associated Three-Gene Prognostic Signature for Patients with Gastric Cancer

Biomed Res Int.

2.279

徐州市中心医院等

42

hsa_circ_0001445的过表达逆转了oxLDL通过SRSF1诱导的HUVEC增殖抑制

Overexpression of hsa_circ_0001445 reverses oxLDL鈥慽nduced inhibition of HUVEC proliferation via SRSF1

Mol Med Rep.

2.102

浙江大学医学院附属第二医院等

43

环状RNA与喉癌的作用及其作用机制

Role and mechanism of action of circular RNA and laryngeal cancer

Pathol Res Pract.Review

2.05

临沂市中心医院等

44

环状RNA circ_0000712通过靶向miR-879-5p/SOX6轴来调节高葡萄糖诱导的（DN）细胞凋亡，炎症，氧化应激和纤维化

Circular RNA circ_0000712 regulates high glucose-induced apoptosis, inflammation, oxidative stress, and fibrosis in (DN) by targeting the miR-879-5p/SOX6 axis

Endocr J.

1.95

湖北医药学院附属东风医院等

45

使用微阵列分析确定婴儿血管瘤患者血浆中的环状RNA表达谱

Circular RNA expression profiles in the plasma of patients with infantile hemangioma determined using microarray analysis

Exp Ther Med.

1.786

山东省立医院等

46

环状RNA circ_0128846通过调节miR-127-5p/NAMPT轴促进骨关节炎的进展

Circular RNA circ_0128846 promotes the progression of osteoarthritis by regulating miR-127-5p/NAMPT axis

J Orthop Surg Res.

1.779

宝鸡市中心医院等

47

CircASH2L通过类风湿关节炎中的miR-129-5p/HIPK2轴促进肿瘤样生物学行为和成纤维样滑膜细胞炎症

CircASH2L facilitates tumor-like biologic behaviours and inflammation of fibroblast-like synoviocytes via miR-129-5p/HIPK2 axis in rheumatoid arthritis

J Orthop Surg Res.

1.776

东营市人民医院等

48

CircMKLN1通过调节miR-425-5p/PDCD4轴抑制人类视网膜母细胞瘤的进展

CircMKLN1 Suppresses the Progression of Human Retinoblastoma by Modulation of miR-425-5p/PDCD4 Axis

Curr Eye Res.

1.753

随州市中心医院等

49

CircRNA表达谱和生物信息学分析表明circRNA在甲型流感病毒诱导的肺损伤中的潜在生物学作用和临床意义

CircRNA expression profiling and bioinformatics analysis indicate the potential biological role and clinical significance of circRNA in influenza A virus-induced lung injury

J Biosci.

1.645

苏州大学附属第一医院等

50

环状RNA_0015278较高与甲状腺乳头状癌患者的甲状腺外侵犯，较低的病理肿瘤分期和无病生存期延长有关

Higher circular RNA_0015278 correlates with absence of extrathyroidal invasion, lower pathological tumor stages, and prolonged disease-free survival in papillary thyroid carcinoma patients

J Clin Lab Anal.

1.544

承德医学院附属医院等

51

阻断circ_UBR4可抑制动脉粥样硬化中人血管平滑肌细胞的增殖，迁移和细胞周期进程

Blocking circ_UBR4 suppressed proliferation, migration, and cell cycle progression of human vascular smooth muscle cells in atherosclerosis

Open Life Sci.

0.691

大连大学中山附属医院等

52

使用综合生物信息学方法研究大肠癌中circRNA-miRNA-mRNA网络

Investigation of circRNA-miRNA-mRNA network in colorectal cancer using an integrative bioinformatics approach

Investigat

0

德黑兰医科大学等