2021年5月circRNA研究汇总-3（ 20210517-0523）

序号

主要内容

论文标题

杂志

影响因子

单位

1

环状RNA在真核生物中广泛存在

Widespread occurrence of circular RNA in eukaryotes

Nat Rev Genet.

33.133

罗马大学等

2

靶向环状RNA作为治疗方法：当前的策略和挑战

Targeting circular RNAs as a therapeutic approach: current strategies and challenges

Signal Transduct Target Ther.

13.493

多伦多大学等

3

环状RNA在衰老中的新兴功能

Emerging functions of circular RNA in aging

Trends Genet.

11.331

韩国高等科学技术学院等

4

M2巨噬细胞衍生的小细胞外囊泡的CircUbe3a介导急性心肌梗死后的心肌纤维化

CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction

Theranostics.

8.579

遵义医科大学附属医院等

5

FMR1 / circCHAF1A / miR-211-5p / HOXC8反馈回路通过MSC2依赖的p53信号传导调节GSC中的增殖和肿瘤发生

FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs

Oncogene.

7.974

上海市第十人民医院等

6

CircRNA VIM沉默与七氟醚协同作用，通过同时调节miR-124 / PD-L1轴来抑制食道癌的免疫逃逸和多种致癌活性

CircRNA VIM silence synergizes with sevoflurane to inhibit immune escape and multiple oncogenic activities of esophageal cancer by simultaneously regulating miR-124/PD-L1 axis

Cell Biol Toxicol.

6.283

苏州大学附属第三医院等

7

环状RNA的最新研究及其在乳腺癌中的潜在临床意义

Current research on circular RNAs and their potential clinical implications in breast cancer

Cancer Biol Med.

5.433

上海市第十人民医院等

8

环形RNA Circ0021205通过MiR-204-5p / RAB22A轴促进胆管癌进展

Circular RNA Circ0021205 Promotes Cholangiocarcinoma Progression Through MiR-204-5p/RAB22A Axis

Front Cell Dev Biol.

5.204

丽水市中心医院等

9

circDENND1B通过miR-17-5p / Abca1轴促进胆固醇外流参与小鼠IL-1β单克隆抗体的抗动脉粥样硬化作用

circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis

Front Cell Dev Biol.

5.204

上海中山医院等

10

上皮-间质转化相关环形RNA，circ-10720在非小细胞肺癌中的作用

Role of the epithelial-mesenchymal transition-related circular RNA, circ-10720, in non-small-cell lung cancer

Transl Lung Cancer Res.

5.13

巴塞罗那大学等

11

circRNA在甲状腺癌和自身免疫性甲状腺疾病中的新兴功能及其临床意义

The emerging function and clinical significance of circRNAs in Thyroid Cancer and Autoimmune Thyroid Diseases

Int J Biol Sci.

4.856

青岛大学医学院等

12

circATP2B1通过调节miR-326基因簇促进胃癌细胞有氧糖酵解

circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster

Front Oncol.

4.846

盛京医院等

13

circRNA在头颈癌中的研究进展

Research Progress of circRNAs in Head and Neck Cancers

Front Oncol.

4.846

中南大学湘雅二医院等

14

环状RNA ABCB10通过调节miR-588 / CXCR4轴促进喉鳞状细胞癌（LSCC）的发展

Circular RNA ABCB10 contributes to laryngeal squamous cell carcinoma (LSCC) progression by modulating the miR-588/CXCR4 axis

Aging (Albany NY).

4.834

沧州市中心医院等

15

椎间盘退变中环状RNA ITCH通过激活Wnt /β-catenin信号传导促进细胞外基质降解

Circular RNA ITCH promotes extracellular matrix degradation via activating Wnt/尾-catenin signaling in intervertebral disc degeneration

Aging (Albany NY).

4.834

上海市光华中西医结合医院等

16

环状RNA_0001495通过海绵吸附microRNA-527增加Robo1表达，从而促进膀胱癌细胞的增殖，迁移和侵袭

Circular RNA_0001495 increases Robo1 expression by sponging microRNA-527 to promote the proliferation, migration and invasion of bladder cancer cells

Carcinogenesis.

4.602

河南大学淮河医院等

17

环状RNA在大肠癌发病机制中的作用

Function of circular RNAs in the pathogenesis of colorectal cancer

Biomed Pharmacother.

4.547

伊朗Shahid Beheshti医科大学

18

环状RNA在甲状腺癌中的研究进展：概述

Advances of circular RNAs in thyroid cancer: An overview

Biomed Pharmacother.

4.547

上海第九人民医院等

19

环状RNA circHECTD1通过miR-137 / PBX3轴预防胃癌中的Diosbulbin-B敏感性

Circular RNA circHECTD1 prevents Diosbulbin-B-sensitivity via miR-137/PBX3 axis in gastric cancer

Cancer Cell Int.

4.179

厦门大学等

20

circRNA、lncRNA、miRNA和mRNA网络在介导睾丸热暴露影响中的综合研究

Integrated study of circRNA, lncRNA, miRNA, and mRNA networks in mediating the effects of testicular heat exposure

Cell Tissue Res.

4.043

蚌埠医学院等

21

使用高效自催化转录本转录RNA以生成杂交环状RNA

Trans ligation of RNAs to generate hybrid circular RNAs using highly efficient autocatalytic transcripts

Methods.

3.813

康奈尔大学等

22

精神疾病中的病毒组研究

Studying the virome in psychiatric disease

Schizophr Res.

3.759

约翰霍普金斯大学等

23

Circ-EGFR通过调节miR-183-5p / TUSC2轴，作为神经胶质瘤恶性进展的抑制因子。

Circ-EGFR Functions as an Inhibitory Factor in the Malignant Progression of Glioma by Regulating the miR-183-5p/TUSC2 Axis

Cell Mol Neurobiol.

3.609

西京医院等

24

外泌体circEPB41L2充当miR-21-5p和miR-942-5p的海绵，通过调节PTEN / AKT信号通路来抑制结直肠癌的进展

Exosomal circEPB41L2 serves as a sponge for miR-21-5p and miR-942-5p to suppress colorectal cancer progression by regulating the PTEN/AKT signalling pathway

Eur J Clin Invest.

3.482

中山大学附属第六医院等

25

使用Chou’s 5-steps法则研究黄芩苷如何抑制恶性表型并诱导大肠癌细胞凋亡

Use Chou’s 5-steps rule to study how Baicalin suppresses the malignant phenotypes and induces the apoptosis of colorectal cancer cells

Arch Biochem Biophys.

3.39

郑州肛肠医院等

26

环状RNA PCDH10通过miR-338-3p / hTERT轴调控胰腺癌的发生

Circular RNA PCDH10 regulates the tumorigenesis of pancreatic cancer through the miR-338-3p/hTERT axis

Am J Transl Res

3.377

枣庄市立医院等

27

CircHIPK2通过circHIPK2 / miR-338-3p / CHTOP ceRNA途径在体内外促进DDP抗性和DDP耐药卵巢癌细胞的恶性行为

CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway

Onco Targets Ther.

3.339

中国医学科学院肿瘤医院等

28

circRNA circVPS33B的抑制作用通过调节浸润性胃癌中的miR-873-5p / HNRNPK轴降低Warburg效应和肿瘤生长

Inhibition of circRNA circVPS33B Reduces Warburg Effect and Tumor Growth Through Regulating the miR-873-5p/HNRNPK Axis in Infiltrative Gastric Cancer

Onco Targets Ther.

3.339

厦门大学附属中山医院等

29

基于RNA表达的系统生物学分析检测circRNA生物标志物在急性心肌梗死中的应用

Detection of circRNA Biomarker for Acute Myocardial Infarction Based on System Biological Analysis of RNA Expression

Front Genet.

3.255

哈尔滨医科大学附属第一医院等

30

NAFLD中circRNA，miRNA和靶基因网络之间的串扰的生物信息学分析

Bioinformatic Analysis of Crosstalk Between circRNA, miRNA, and Target Gene Network in NAFLD

Front Genet.

3.255

中国医科大学附属第四医院等

31

Hsa_circ_0000301通过靶向miR-1228-3p / IRF4轴促进宫颈癌的进展

Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting miR-1228-3p/IRF4 Axis

BMC Cancer.

3.152

武汉大学人民医院等

32

Hsa_circ_0010220通过 miR-198 / Syntaxin 6轴调节骨肉瘤进展

Hsa_circ_0010220 regulates miR-198/Syntaxin 6 axis to promote osteosarcoma progression

J Bone Oncol.

3.065

商丘市第一人民医院等

33

环状RNA circCRIM1通过调节miR-125b-5p / BTG2轴抑制肺腺癌细胞的迁移，侵袭，EMT和糖酵解

Circular RNA circCRIM1 suppresses lung adenocarcinoma cell migration, invasion, EMT, and glycolysis through regulating miR-125b-5p/BTG2 axis

Eur Rev Med Pharmacol Sci.

3.023

河南大学淮河医院等

34

环状RNA hsa_circ_0017247通过诱导Wnt /β-catenin信号传导途径在膀胱癌中作为癌基因

Circular RNA hsa_circ_0017247 acts as an oncogene in bladder cancer by inducing Wnt/尾-catenin signaling pathway

Eur Rev Med Pharmacol Sci.

3.023

上海交通大学医学院附属同仁医院等

35

Circ_HIPK3基因敲低部分通过介导miR-148a-3p / ULK1途径抑制胆管癌的细胞增殖，迁移和侵袭

Circ_HIPK3 Knockdown Inhibits Cell Proliferation, Migration and Invasion of Cholangiocarcinoma Partly via Mediating the miR-148a-3p/ULK1 Pathway

Cancer Manag Res.

2.888

陕西省人民医院等

36

环状RNA circ_CORO1C的耗竭通过调节miR-138-5p / KLF12轴抑制胃癌的发展

Depletion of Circular RNA circ_CORO1C Suppresses Gastric Cancer Development by Modulating miR-138-5p/KLF12 Axis

Cancer Manag Res.

2.888

榆林市第二医院等

37

SARS-CoV-2感染的人肺上皮细胞中差异宿主circRNA表达谱

Differential host circRNA expression profiles in human lung epithelial cells infected with SARS-CoV-2

Infect Genet Evol.

2.772

北京协和医学院等

38

Circ_0001955作为miR-646海绵来促进肝细胞癌的增殖，转移和血管生成

Circ_0001955 Acts as a miR-646 Sponge to Promote the Proliferation, Metastasis and Angiogenesis of Hepatocellular Carcinoma

Dig Dis Sci.

2.751

山西省人民医院等

39

以miRNA为中心的ceRNA调控网络与疲劳之间关系的研究

Study on the Relationship between the miRNA-centered ceRNA Regulatory Network and Fatigue

J Mol Neurosci.

2.679

北京中医药大学等

40

CircJARID2通过影响miR-9-5p介导的BNIP3调节缺氧诱导的H9c2细胞损伤

CircJARID2 regulates hypoxia-induced injury in H9c2 cells by affecting miR-9-5p-mediated BNIP3

J Cardiovasc Pharmacol.

2.597

江西省人民医院等

41

环形RNA PTGR1通过调节miR-129-5p / ABCC1轴调节5-FU耐药性和肝癌细胞的发育

Circular RNA PTGR1 regulates 5-FU resistance and development of hepatocellular carcinoma cells by modulating miR-129-5p/ABCC1 axis

Cell Biol Int.

2.574

天津市肿瘤医院等

42

转录组测序在非小细胞肺癌中的表皮生长因子受体突变机制

Epidermal Growth Factor Receptor Mutation Mechanisms in Nonsmall Cell Lung Cancer by Transcriptome Sequencing

Cancer Biother Radiopharm.

2.312

陕西省人民医院等

43

环形RNA circ_ASAP2通过miR-330-3p / NT5E轴调控对顺铂耐药的胃癌细胞的药物敏感性和功能行为

Circular RNA circ_ASAP2 regulates drug sensitivity and functional behaviors of cisplatin-resistant gastric cancer cells by the miR-330-3p/NT5E axis

Anticancer Drugs.

2.261

胜利油田中心医院等

44

姜黄素通过调节circ-FNDC3B / miR-138-5p / IGF2轴抑制肾癌的肿瘤发生

Curcumin suppresses renal carcinoma tumorigenesis by regulating circ-FNDC3B/miR-138-5p/IGF2 axis

Anticancer Drugs.

2.261

南通市中医院等

45

环状RNA circ_0008274通过海绵化microRNA -140-3p上调颗粒蛋白以促进肝细胞癌的进展

Circular RNA circ_0008274 upregulates granulin to promote the progression of hepatocellular carcinoma via sponging microRNA -140-3p

Bioengineered.

2.209

南京鼓楼医院等

46

脂多糖诱导的MRC-5细胞急性肺损伤模型中的新型环状RNA（hsa_circ_0059930）介导的miRNA-mRNA轴

A novel circular RNA (hsa_circ_0059930)-mediated miRNA-mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells

Bioengineered.

2.209

中山大学附属第三医院等

47

CircRNA 010567通过调节miRNA-141 / DAPK1轴在心肌梗死中起重要作用

CircRNA 010567 plays a significant role in myocardial infarction via the regulation of the miRNA-141/DAPK1 axis

J Thorac Dis.

2.046

中国人民解放军第983医院等

48

CircPAG1通过海绵吸附miR-630并上调EPHA2抑制高糖诱导的晶状体上皮细胞损伤

CircPAG1 inhibits the high glucose-induced lens epithelial cell injury by sponging miR-630 and upregulating EPHA2

Curr Eye Res.

1.752

台州中心医院等

49

circ_0004913、circ_0008160、circ_0000517失调及其作为肝癌疾病监测和预后生物标志物的潜力

Dysregulated circ_0004913, circ_0008160, circ_0000517, and their potential as biomarkers for disease monitoring and prognosis in hepatocellular carcinoma

J Clin Lab Anal.

1.54

南华大学附属南华医院等

50

Circ_0038467通过MR-195通路通过MR-195通路调控miR-195-5p / TLR4轴介导的脂多糖介导的细胞增殖、凋亡和炎症反应

Circ_0038467 regulates lipopolysaccharide-mediated cell proliferation, apoptosis and inflammatory response by miR-195-5p/TLR4 axis through NF-魏B pathway in MRC-5 cells

Biosci Biotechnol Biochem.

1.519

河北医科大学第三医院等

51

抑制环状RNA circGFRA1通过上调microRNA-99a抑制神经胶质瘤细胞的增殖和迁移

Knockdown circular RNA circGFRA1 inhibits glioma cell proliferation and migration by upregulating microRNA-99a

Neuroreport.

1.392

齐齐哈尔医院等

52

circAGFG1通过调节HIF-1α水平使miR-28-5p促进非小细胞肺癌的进展

circAGFG1 sponges miR-28-5p to promote non-small-cell lung cancer progression through modulating HIF-1伪 level

Open Med (Wars).

1.204

陕西省核工业二一五医院等

53

circ_0037655的下调通过miR-1229-3p / ITGB8轴阻止神经胶质瘤的形成和转移

Downregulation of circ_0037655 impedes glioma formation and metastasis via the regulation of miR-1229-3p/ITGB8 axis

Open Life Sci.

0.692

海南省肿瘤医院等